Home > NY > Erie County > Buffalo > Zip 14221

Zip Code 14221 — Buffalo, NY

14221 is a ZIP Code associated with Buffalo, NY, located within Erie. 14221 ranks #1 out of 68 ZIP codes in Erie County by population (and #74 out of 1,826 in NY). The area supports an estimated population of 55,255 residents across Data Pending housing units, with a population density of 912.1 people per square mile.
WorldPlaceData database updated: October 2026

📍 View location on OpenStreetMap (42.979180, -78.721580)

Data MetricLocal Statistic
Postal / Zip Code14221
Primary CityBuffalo
State / ProvinceNY
CountyErie
Total Population55,255
Median Household IncomeData Pending
Total Housing UnitsData Pending
Population Density912.1 people/sq mi
TimezoneAmerica/New_York

How 14221 Compares

MetricZIP 14221Erie CountyNY State Average
Population55,255950,963 (Total)19,771,902 (Total)
Average ZIP IncomeData PendingN/AN/A
Population Density912.1 /sq mi----
County Pop Rank#1 of 68----

Nearby ZIP Codes

ZIP CodeCityDistancePopulationMedian Income
Zip 14026Bowmansville3.1 mi617N/A
Zip 14261Buffalo3.6 mi5,033N/A
Zip 14068Getzville3.8 mi8,636N/A
Zip 14225Buffalo3.8 mi33,620N/A
Zip 14260Buffalo3.8 mi924N/A

Data Sources & Methodology: Geographic coordinates and ZIP Code assignments are derived from underlying geographic and postal datasets. Note that ZIP Codes are USPS postal delivery areas, while Census ZCTAs are statistical approximation areas. Read full methodology →