Zip Code 49221 — Adrian, MI
49221 is a ZIP Code associated with Adrian, MI, located within Lenawee. The postal region supports an estimated population of 41,087 residents across Data Pending housing units, with a population density of 132.3 people per square mile.
WorldPlaceData database updated: October 2026
📍 View location on OpenStreetMap (41.903430, -84.063720)
| Data Metric | Local Statistic |
|---|
| Postal / Zip Code | 49221 |
| Primary City | Adrian |
| State / Province | MI |
| County | Lenawee |
| Total Population | 41,087 |
| Median Household Income | Data Pending |
| Total Housing Units | Data Pending |
| Population Density | 132.3 people/sq mi |
| Timezone | America/Detroit |
How 49221 Compares
| Metric | ZIP 49221 | Lenawee County | MI State Average |
|---|
| Population | 41,087 | 98,534 | 10,077,716 |
| Median Income | Data Pending | N/A | N/A |
| Population Density | 132.3 /sq mi | -- | -- |
Nearby ZIP Codes
Data Sources & Methodology: Geographic coordinates and ZIP Code assignments are derived from underlying geographic and postal datasets. Note that ZIP Codes are USPS postal delivery areas, while Census ZCTAs are statistical approximation areas. Read full methodology →